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  "BRCA2 anchors BRCA1 and BRCA1 anchors BRCA2; this is a two-gene fallback, not the broad-panel clinical model.",
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  "A simultaneous BRCA1/BRCA2 dosage shift remains non-identifiable."
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   ],
   "reasons": []
  },
  {
   "sample": "HG02266",
   "status": "NO_CALL_QC",
   "calls": [],
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    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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   "reasons": [
    "BRCA1: control log2 noise 0.195 exceeds 0.190"
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  },
  {
   "sample": "HG02292",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": []
  },
  {
   "sample": "HG02307",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": []
  },
  {
   "sample": "HG02312",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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   "reasons": []
  },
  {
   "sample": "HG02317",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": []
  },
  {
   "sample": "HG02360",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": []
  },
  {
   "sample": "HG02386",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": []
  },
  {
   "sample": "HG02389",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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   "reasons": []
  },
  {
   "sample": "HG02521",
   "status": "NO_CALL_QC",
   "calls": [],
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    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": [
    "BRCA1: control log2 noise 0.206 exceeds 0.190"
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  },
  {
   "sample": "HG02561",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": []
  },
  {
   "sample": "HG02580",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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   "reasons": []
  },
  {
   "sample": "HG02601",
   "status": "REFLEX_POSITIVE",
   "calls": [
    {
     "gene": "BRCA1",
     "kind": "DEL",
     "first_exon": "6",
     "last_exon": "6",
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     "n_targets": 1,
     "mean_log2": -0.8381,
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     "threshold": 4.1925,
     "disposition": "REFLEX_POSITIVE"
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    {
     "gene": "BRCA2",
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     "last_exon": "18",
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      "BRCA2_E18"
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     "n_targets": 2,
     "mean_log2": 0.4981,
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     "threshold": 4.6351,
     "disposition": "REFLEX_POSITIVE"
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    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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   "reasons": []
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  {
   "sample": "HG02610",
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    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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   "reasons": []
  },
  {
   "sample": "HG02757",
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   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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   "reasons": []
  },
  {
   "sample": "HG02768",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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   "reasons": []
  },
  {
   "sample": "HG02775",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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   "reasons": []
  },
  {
   "sample": "HG02804",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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   "reasons": []
  },
  {
   "sample": "HG02811",
   "status": "NO_CALL_QC",
   "calls": [],
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    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": [
    "BRCA2: control log2 noise 0.273 exceeds 0.221"
   ]
  },
  {
   "sample": "HG02944",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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   "reasons": []
  },
  {
   "sample": "HG03085",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": []
  },
  {
   "sample": "HG03091",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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   "reasons": []
  },
  {
   "sample": "HG03130",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": []
  },
  {
   "sample": "HG03169",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": []
  },
  {
   "sample": "HG03238",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": []
  },
  {
   "sample": "HG03246",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": []
  },
  {
   "sample": "HG03258",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": []
  },
  {
   "sample": "HG03401",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": []
  },
  {
   "sample": "HG03442",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": []
  },
  {
   "sample": "HG03594",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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   "reasons": []
  },
  {
   "sample": "HG03595",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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   "reasons": []
  },
  {
   "sample": "HG03640",
   "status": "NO_CALL_QC",
   "calls": [],
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    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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   "reasons": [
    "BRCA2: control log2 noise 0.227 exceeds 0.221"
   ]
  },
  {
   "sample": "HG03646",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
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    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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   "reasons": []
  },
  {
   "sample": "HG03660",
   "status": "NO_CALL_QC",
   "calls": [],
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    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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   "reasons": [
    "BRCA2: control log2 noise 0.264 exceeds 0.221"
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  },
  {
   "sample": "HG03698",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": []
  },
  {
   "sample": "HG03744",
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   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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   "reasons": []
  },
  {
   "sample": "HG03750",
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   "calls": [],
   "excluded_targets": [
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    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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   "reasons": []
  },
  {
   "sample": "HG03767",
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   "calls": [],
   "excluded_targets": [
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    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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   "reasons": []
  },
  {
   "sample": "HG03785",
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   "calls": [],
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    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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   "reasons": []
  },
  {
   "sample": "HG03800",
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    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": [
    "BRCA2: control log2 noise 0.235 exceeds 0.221"
   ]
  },
  {
   "sample": "HG03833",
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   "excluded_targets": [
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    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": []
  },
  {
   "sample": "HG03897",
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    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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   "reasons": []
  },
  {
   "sample": "HG03920",
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    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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   "reasons": []
  },
  {
   "sample": "HG03943",
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    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": []
  },
  {
   "sample": "HG03949",
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    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": [
    "BRCA1: control log2 noise 0.202 exceeds 0.190"
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  },
  {
   "sample": "HG03953",
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    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": [
    "BRCA2: control log2 noise 0.253 exceeds 0.221"
   ]
  },
  {
   "sample": "HG04158",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
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    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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   "reasons": []
  },
  {
   "sample": "HG04194",
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   "calls": [],
   "excluded_targets": [
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    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": []
  },
  {
   "sample": "NA12275",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
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    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": []
  },
  {
   "sample": "NA12776",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
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    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": []
  },
  {
   "sample": "NA12829",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": []
  },
  {
   "sample": "NA18502",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": []
  },
  {
   "sample": "NA18552",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": []
  },
  {
   "sample": "NA18573",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
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    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": []
  },
  {
   "sample": "NA18609",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
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    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": []
  },
  {
   "sample": "NA18611",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
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    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": []
  },
  {
   "sample": "NA18632",
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   "calls": [],
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    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": []
  },
  {
   "sample": "NA18643",
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    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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   "reasons": [
    "BRCA1: control log2 noise 0.232 exceeds 0.190",
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  },
  {
   "sample": "NA18645",
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   "calls": [
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     "gene": "BRCA2",
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     "last_exon": "17",
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     "mean_log2": -0.6527,
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   ],
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   "reasons": []
  },
  {
   "sample": "NA18971",
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    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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   "reasons": []
  },
  {
   "sample": "NA18972",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
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    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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   "reasons": []
  },
  {
   "sample": "NA19000",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
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    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": []
  },
  {
   "sample": "NA19003",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
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    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": []
  },
  {
   "sample": "NA19091",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": []
  },
  {
   "sample": "NA19096",
   "status": "NO_CALL_QC",
   "calls": [],
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    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": [
    "BRCA1: control log2 noise 0.234 exceeds 0.190"
   ]
  },
  {
   "sample": "NA19131",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": []
  },
  {
   "sample": "NA19153",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
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    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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   "reasons": []
  },
  {
   "sample": "NA19172",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": []
  },
  {
   "sample": "NA19395",
   "status": "NO_CALL_QC",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": [
    "BRCA1: control log2 noise 0.201 exceeds 0.190"
   ]
  },
  {
   "sample": "NA19446",
   "status": "NO_CALL_QC",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": [
    "BRCA1: control log2 noise 0.208 exceeds 0.190",
    "BRCA2: control log2 noise 0.295 exceeds 0.221"
   ]
  },
  {
   "sample": "NA19474",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": []
  },
  {
   "sample": "NA19678",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": []
  },
  {
   "sample": "NA19704",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": []
  },
  {
   "sample": "NA19726",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": []
  },
  {
   "sample": "NA19728",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": []
  },
  {
   "sample": "NA19749",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": []
  },
  {
   "sample": "NA19758",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": []
  },
  {
   "sample": "NA19759",
   "status": "REFLEX_POSITIVE",
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    {
     "gene": "BRCA2",
     "kind": "DEL",
     "first_exon": "2",
     "last_exon": "2",
     "target_ids": [
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     "n_targets": 1,
     "mean_log2": -1.42,
     "statistic": 6.2685,
     "threshold": 4.6351,
     "disposition": "REFLEX_POSITIVE"
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   ],
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    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": []
  },
  {
   "sample": "NA19761",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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   "reasons": []
  },
  {
   "sample": "NA19762",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
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    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": []
  },
  {
   "sample": "NA20346",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": []
  },
  {
   "sample": "NA20520",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": []
  },
  {
   "sample": "NA20529",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": []
  },
  {
   "sample": "NA20530",
   "status": "REFLEX_POSITIVE",
   "calls": [
    {
     "gene": "BRCA1",
     "kind": "DUP",
     "first_exon": "15",
     "last_exon": "22",
     "target_ids": [
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      "BRCA1_E16",
      "BRCA1_E17",
      "BRCA1_E18",
      "BRCA1_E19",
      "BRCA1_E20",
      "BRCA1_E21",
      "BRCA1_E22"
     ],
     "n_targets": 8,
     "mean_log2": 0.5652,
     "statistic": 5.0517,
     "threshold": 4.1925,
     "disposition": "REFLEX_POSITIVE"
    }
   ],
   "excluded_targets": [
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    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": []
  },
  {
   "sample": "NA20534",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": []
  },
  {
   "sample": "NA20538",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": []
  },
  {
   "sample": "NA20539",
   "status": "NO_CALL_QC",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": [
    "BRCA1: control log2 noise 0.205 exceeds 0.190"
   ]
  },
  {
   "sample": "NA20799",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": []
  },
  {
   "sample": "NA20813",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": []
  },
  {
   "sample": "NA20821",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": []
  },
  {
   "sample": "NA20854",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": []
  },
  {
   "sample": "NA20869",
   "status": "NO_CALL_QC",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": [
    "BRCA2: control log2 noise 0.240 exceeds 0.221"
   ]
  },
  {
   "sample": "NA20904",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": []
  },
  {
   "sample": "NA21108",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": []
  },
  {
   "sample": "NA21120",
   "status": "NO_CALL_QC",
   "calls": [
    {
     "gene": "BRCA2",
     "kind": "DEL",
     "first_exon": "13",
     "last_exon": "13",
     "target_ids": [
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     "n_targets": 1,
     "mean_log2": -2.3204,
     "statistic": 7.0365,
     "threshold": 4.6351,
     "disposition": "REFLEX_POSITIVE"
    }
   ],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": [
    "BRCA1: control log2 noise 0.230 exceeds 0.190"
   ]
  },
  {
   "sample": "NA21129",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": []
  },
  {
   "sample": "NA21137",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": []
  }
 ],
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  "NO_CALL_QC": 21,
  "REFLEX_POSITIVE": 5
 },
 "evidence_operational_results": [
  {
   "sample": "HG00116",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": [],
   "source_median_target_depth": 75.9
  },
  {
   "sample": "HG00117",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": [],
   "source_median_target_depth": 41.3
  },
  {
   "sample": "HG00132",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": [],
   "source_median_target_depth": 47.2
  },
  {
   "sample": "HG00149",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": [],
   "source_median_target_depth": 48.5
  },
  {
   "sample": "HG00150",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": [],
   "source_median_target_depth": 54.9
  },
  {
   "sample": "HG00243",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": [],
   "source_median_target_depth": 71.9
  },
  {
   "sample": "HG00271",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": [],
   "source_median_target_depth": 126.1
  },
  {
   "sample": "HG00275",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": [],
   "source_median_target_depth": 105.1
  },
  {
   "sample": "HG00306",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": [],
   "source_median_target_depth": 37.8
  },
  {
   "sample": "HG00376",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": [],
   "source_median_target_depth": 91.5
  },
  {
   "sample": "HG00473",
   "status": "NO_CALL_QC",
   "calls": [],
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    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": [
    "BRCA1: control log2 noise 0.371 exceeds 0.190",
    "BRCA2: control log2 noise 0.274 exceeds 0.221"
   ],
   "source_median_target_depth": 60.1
  },
  {
   "sample": "HG00593",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": [],
   "source_median_target_depth": 67.6
  },
  {
   "sample": "HG00693",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": [],
   "source_median_target_depth": 123.3
  },
  {
   "sample": "HG00708",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": [],
   "source_median_target_depth": 114.4
  },
  {
   "sample": "HG01052",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": [],
   "source_median_target_depth": 129.5
  },
  {
   "sample": "HG01107",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": [],
   "source_median_target_depth": 150.1
  },
  {
   "sample": "HG01113",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": [],
   "source_median_target_depth": 96.9
  },
  {
   "sample": "HG01130",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": [],
   "source_median_target_depth": 121.1
  },
  {
   "sample": "HG01139",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": [],
   "source_median_target_depth": 55.8
  },
  {
   "sample": "HG01173",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": [],
   "source_median_target_depth": 111.7
  },
  {
   "sample": "HG01271",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": [],
   "source_median_target_depth": 62.0
  },
  {
   "sample": "HG01280",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": [],
   "source_median_target_depth": 86.9
  },
  {
   "sample": "HG01334",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": [],
   "source_median_target_depth": 97.7
  },
  {
   "sample": "HG01345",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": [],
   "source_median_target_depth": 54.5
  },
  {
   "sample": "HG01384",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": [],
   "source_median_target_depth": 48.6
  },
  {
   "sample": "HG01461",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": [],
   "source_median_target_depth": 32.4
  },
  {
   "sample": "HG01464",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": [],
   "source_median_target_depth": 34.6
  },
  {
   "sample": "HG01578",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": [],
   "source_median_target_depth": 135.5
  },
  {
   "sample": "HG01596",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": [],
   "source_median_target_depth": 127.6
  },
  {
   "sample": "HG01608",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": [],
   "source_median_target_depth": 58.5
  },
  {
   "sample": "HG01618",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": [],
   "source_median_target_depth": 65.6
  },
  {
   "sample": "HG01632",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
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   "sample": "HG01670",
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   "sample": "HG01802",
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    "BRCA1_E23",
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   "sample": "HG01840",
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   "sample": "HG01841",
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    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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   "sample": "HG01869",
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    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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   "sample": "HG01870",
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      "BRCA2_E24"
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     "threshold": 4.6351,
     "disposition": "REFLEX_POSITIVE"
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    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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   "sample": "HG01885",
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    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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   "sample": "HG01923",
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    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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   "sample": "HG01924",
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    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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   "sample": "HG01942",
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    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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   "sample": "HG01950",
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    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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   "sample": "HG01982",
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    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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   "sample": "HG01988",
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    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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    "BRCA2: control log2 noise 0.229 exceeds 0.221"
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   "sample": "HG02061",
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    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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   "sample": "HG02069",
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    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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   "sample": "HG02154",
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    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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   "sample": "HG02187",
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    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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    "BRCA1: control log2 noise 0.211 exceeds 0.190"
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   "sample": "HG02235",
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    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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   "sample": "HG02252",
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    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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   "sample": "HG02266",
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    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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    "BRCA1: control log2 noise 0.195 exceeds 0.190"
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   "sample": "HG02292",
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    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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  {
   "sample": "HG02307",
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    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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  {
   "sample": "HG02312",
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    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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  {
   "sample": "HG02317",
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    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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  {
   "sample": "HG02360",
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    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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  {
   "sample": "HG02386",
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    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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   "reasons": [],
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   "sample": "HG02389",
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    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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   "sample": "HG02521",
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    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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   "sample": "HG02561",
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    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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   "sample": "HG02580",
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    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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   "sample": "HG02601",
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     "threshold": 4.1925,
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      "BRCA2_E18"
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     "threshold": 4.6351,
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   "sample": "HG02610",
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    "BRCA1_E23",
    "BRCA2_E01"
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   "sample": "HG02757",
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    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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   "sample": "HG02768",
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    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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   "sample": "HG02775",
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    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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   "sample": "HG02804",
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    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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   "sample": "HG02811",
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    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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   "sample": "HG02944",
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    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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   "sample": "HG03022",
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    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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   "source_median_target_depth": 24.1
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  {
   "sample": "HG03085",
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    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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   "sample": "HG03091",
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    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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   "sample": "HG03130",
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    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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  {
   "sample": "HG03169",
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    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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  {
   "sample": "HG03238",
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    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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  {
   "sample": "HG03246",
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    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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  {
   "sample": "HG03258",
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    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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  {
   "sample": "HG03401",
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    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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  {
   "sample": "HG03442",
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    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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  {
   "sample": "HG03594",
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    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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  {
   "sample": "HG03595",
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    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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   "sample": "HG03640",
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    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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  {
   "sample": "HG03646",
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    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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   "sample": "HG03660",
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    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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  {
   "sample": "HG03698",
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    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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  {
   "sample": "HG03744",
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    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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  {
   "sample": "HG03750",
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    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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  {
   "sample": "HG03767",
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    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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   "reasons": [],
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  {
   "sample": "HG03785",
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    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
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   "source_median_target_depth": 129.4
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  {
   "sample": "HG03800",
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     "target_ids": [
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     ],
     "n_targets": 1,
     "mean_log2": -2.3204,
     "statistic": 7.0365,
     "threshold": 4.6351,
     "disposition": "REFLEX_POSITIVE"
    }
   ],
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    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
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   ],
   "reasons": [
    "BRCA1: control log2 noise 0.230 exceeds 0.190"
   ],
   "source_median_target_depth": 32.6
  },
  {
   "sample": "NA21129",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
    "BRCA1_E11",
    "BRCA1_E23",
    "BRCA2_E01"
   ],
   "reasons": [],
   "source_median_target_depth": 35.5
  },
  {
   "sample": "NA21137",
   "status": "NO_CANDIDATE_PARTIAL_COVERAGE",
   "calls": [],
   "excluded_targets": [
    "BRCA1_E01",
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    "BRCA2_E01"
   ],
   "reasons": [],
   "source_median_target_depth": 69.5
  }
 ],
 "environment": {
  "python": "3.14.6",
  "numpy": "2.5.1"
 }
}