{
  "schema_version": "1.0",
  "audit_date": "2026-08-01",
  "scope": {
    "service": "Dropbox web application",
    "folder": "/Yang Shao/Personal/Codexhome/Bioinformatics",
    "note": "This is the online Dropbox folder, not an inference from the partially synchronized local mirror."
  },
  "definition": "A qualifying file is a complete whole-exome sequencing alignment, not a BRCA or other regional slice, targeted panel, simulated/derived cohort file, demonstration file, or spike-in.",
  "methods": {
    "searches": [
      ".bam",
      ".fastq.gz",
      ".fq.gz",
      ".cram",
      ".sra",
      "exome",
      "whole exome",
      "WES"
    ],
    "bam_search_completion_check": "Scrolled through the exact .bam result block until Dropbox began returning only .bam.bai and other substring matches; two additional scroll cycles produced no new exact .bam files.",
    "local_cross_check": "A recursive local file-name and size scan was used only as a secondary check because Smart Sync does not guarantee that every online item is local."
  },
  "results": {
    "exact_bam_files_online": 342,
    "bam_classification": {
      "LGASieve_BRCA_region_mini_BAM": 150,
      "LGASieve_synthetic_or_derived_cohort_BAM": 117,
      "LGASieve_other_mini_BAM": 20,
      "LGASieve_demo_BAM": 1,
      "SpikeForge_spike_in_BAM": 54
    },
    "largest_bam": {
      "name": "F1502261887_S18.spiked.bam",
      "bytes_displayed_by_dropbox": "649.95 MB",
      "classification": "SpikeForge spike-in, not an original complete WES alignment"
    },
    "smallest_bam": {
      "name": "HG03022 BRCA mini-BAM",
      "bytes_displayed_by_dropbox": "787.05 KB"
    },
    "fastq_gz_results_online": 154,
    "fastq_interpretation": "The visible files are small FusionSieve diagnostic/cohort/test artifacts (largest approximately 43.69 MB), not complete human WES read sets.",
    "cram_results_online": 0,
    "fq_gz_results_online": 0,
    "sra_results_online": 0,
    "whole_exome_exact_phrase_results_online": 0,
    "complete_wes_alignment_files_online": 0
  },
  "important_nonqualifying_items": {
    "full_exome_bai_indexes": "The exome search returned indexes for official 1000 Genomes exome BAMs in an _bai directory, but the corresponding full multi-gigabyte BAMs are not stored in Dropbox.",
    "mini_bam_sources": "Source manifests point to official remote 1000 Genomes full exome BAMs; the Dropbox BAMs themselves contain only selected regions."
  },
  "conclusion": "No complete whole-exome BAM, CRAM, FASTQ pair, or SRA object was found in the audited online Dropbox Bioinformatics folder."
}